the information site on endocrine disruption
 











 

Categories

General
Breast Cancer
Endometrial Cancer
Endometriosis
Fertility-fecundity
Immune System
Male Reproductive Tract Abnormalities
Neurodevelopment
Ovarian Cancer
Precocious Puberty
Prostate Cancer
Semen Quality
Sex Ratios
Spontaneous Abortion
Testicular Cancer
Thyroid



General


Summary of endocrine disruption research January to June 2007

Inherited effects of endocrine disruptors

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility. Anway, M.; Cupp, A.; Uzumcu, M.; and Skinner, M. Science (308):1466-1469, 2005. PM: 15933200.

Arctic Seabirds and Pond Contamination
Arctic Seabirds Transport Marine-Derived Contaminants. Blais JM, Kimpe LE, McMahon D, Keatley BE, Mallory ML, Douglas MS, Smol JP. Science. 309: 445, 2005. PM: 16020729.

See also Interview with Dr. Blais

BPA and reproductive health

Endocrine disruptors and reproductive health: The case of bisphenol A. Maffini, M.V., Rubin, B.S., Sonnenschein, C., Soto, A.M. Molecular and Cellular Endocrinology 25:179-186. 2006. PM: 16781053

Detection of organochlorine compounds in breast milk in Czech mothers. Cajka, T, Hajslova J. Polychlorinated biphenyls and organochlorine pesticides in human milk from the locality Prague, Czech Republic: A comparative study. Bulletin Environmental Contamination and Toxicology. 70:913-919. 2003. PM:12719815

Health concerns in areas of environmental contamination
Incidence of endocrine disease among residents of New York areas of concern.
Carpenter DO, Shen Y, Nguyen T, Le L, Lininger LL. Environmental Health Perspectives. Suppl. 6: 845-851. 2001. PM:11744502

Bisphenol A and Low Dose Effects Weight of the evidence evaluation of low-dose reproductive and developmental effects of Bisphenol A. Gray, G.M., Cohen, J.T., Cunha, G., Hughes, C., McConnell, E.E., Rhomberg, L., Sipes I.G., Mattison, D. Human and Ecological Risk Assessment, 10: 875-921, 2004.

Cadmium- the new endocrine disrupter? Johnson, M.D., Kenney, N., Stoica, A., Hilakivi-Clarke, L., Singh, B., Chepko, G., Clarke, R., Sholler, P.F., Lirio, A.A., Foss, C., Reiter, R., Trock, B., Paik, S., Martin, M. Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nature Medicine. Advance Online Publication. 13 July 2003.

TCDD exposure and birth outcomes
Paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and birth outcomes of offspring: birth weight, preterm delivery, and birth defects. Lawson, C., Schnorr, T., Whelan, E., Deddens, J., Dankovic, D, Piacitelli, L., Sweeney, M., and Connally, L. Environmental Health Perspectives. 112(14):1403-1408. PM: 15471733

Exposure to pesticides and risk of childhood leukemia
Critical windows of exposure to household pesticides and risk of childhood leukemia. Ma X, Buffler PA, Gunier RB, Dahl G, Smith MT, Reinier K, Reynolds P. Environ Health Perspect. 2002; 110(9):955-60.
PM:12204832

Topical application of coal tar induces tumour formation in mice
Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis.
Marston CP, Pereira C, Ferguson J, Fischer K, Hedstrom O, Dashwood W-M, Baird WM. Carcinogenesis 22:1077-1086. 2001. PM:11408352

Maternal sport fish consumption and birth defects by sex of offspring
Birth defects risk associated with maternal sport fish consumption: potential effect modification by sex of offspring. Mendola P, Robinson LK, Buck GM, Druschel CM, Fitzgerald EF, Sever LE, Vena JE. Environmental Research 97(2):134-141, 2005. PM: 15533329.

Birth outcomes following in utero exposure to environmental pollutants
Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population.
Perera, FP., Rauh, V., Tsai, W., Kinney, P., Camann, D., Barr, D., Bernert, T., Garfinkel, R., Tu, Y., Diaz, D., Dietrich, J., Whyatt, RM. Environmental Health Perspectives, 111 (2): 201-205; 2003. PM:12573906

Xenoestrogen exposure via dietary intake
A review of the potential impact of dietary endocrine disruptors on the consumer.
Shaw I, McCully S. International Journal of Food Science and Technology 37:471-476, 2002.

Bisphenol A. Current Need for a New Risk Assessment
An Extensive New Literature Concerning Low-Dose Effects of Bisphenol A Shows the Need for a New Risk Assessment. Vom Saal FS and Hughes C. Environmental Health Perspectives: 113(8):926-933, 2005. PM: 16079060.


Breast cancer

Endocrine disrupting effects of cigarette smoke and risk of breast cancer
Carcinogenic and endocrine disrupting effects of cigarette smoke and risk of breast cancer.
Band PR, Le ND, Fang R, Deschamps M. Lancet 360(9339):1044, 2002. PM:12383984

Breast cancer risk and pesticide exposure
Breast cancer risk and historical exposure to pesticides from wide-area applications assessed with GIS. Brody JG., Aschengrau A., McKelvey W., Rudel RA., Swartz CH., Kennedy T. Environmental Health Perspectives 112(8):889-897, 2004. PM: 15175178.

Relationship between serum organochlorines and breast cancer. Charlier C, Albert A, Herman P, Hamoir E, Gaspard U, Meurisse M, Plomteux G. Breast cancer and serum organochlorine residues. Occupational and Environmental Medicine. 60:348-351. 2003. PM:12709520

Breast cancer and pesticide use
Pesticide Use and Breast Cancer Risk Among Farmers’ Wives in the Agricultural Health Study. Engel L.S., Hill D.A., Hoppin J.A., Lubin J.H., Lynch C.F., Pierce J., Samanic C., Sandler D.P., Blair A., Alavanja, M.C. American Journal of Epidemiology 161: 121-135, 2005. PM: 15632262.

Rat mammary gland development is sensitive to dioxin exposure
Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8 - tetrachlorodibenzo-p-dioxin (TCDD).
Fenton SE, Hamm JT, Birnbaum LS, Youngblood GL. Toxicological Sciences (67):63-74, 2002. PM:11961217

Exposure to herbicide atrazine and risk of breast and ovarian cancer
Regional assessment of Atrazine exposure and incidence of breast and ovarian cancers in Kentucky.
Hopenhayn-Rich C, Stump ML, Browning SR. Browning Archives of Environmental Contamination and Toxicology. 42:127-136. 2001. PM:11706377

Breast cancer and agricultural pesticide use
Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers cohort. Reynolds P, Hurley SE, Goldberg DE, Yerabati S, Gunier RB, Hertz A, Anton-Culver H, Bernstein L, Deapen D, Horn-Ross PL, Peel D, Pinder R, Ross RK, West D, Wright WE, Ziogas A. Environmental Research 96: 206-218, 2004. PM: 15325881.

Organochlorines and breast cancer risk
Organochlorines and breast cancer risk by receptor status, tumor size, and grade (Canada).
Woolcott CG, Aronson KJ, Hanna WM, SenGupta SK, McCready DR, Sterns EE, Miller AB. Cancer Causes and Control, 12: 395-404, 2001 PM:11545454

PCBs, genetic polymorphisms and breast cancer risk
Serum Polychlorinated Biphenyls, Cytochrome P-450 1A1 Polymorphisms, and Risk of Breast Cancer in Connecticut Women. Zhang Y., Piece Wise J., Holford T., Zie H., Boyle P., Hoar Zahm S., Rusiecki J., Zou K., Zhang B., Zhu Y., Owens P., and Zheng T. American Journal of Epidemiology. 160: 1177-1183, 2004. PM: 15583370

Endometrial cancer

Endometriosis and dioxin exposure
The risk of endometriosis and exposure to dioxins and polychlorinated biphenyls: a case control study of infertile women. Pauwels A, Schepens PJC, Hooghe TD, Delbeke L, Brouwer L, Weyler J. Human Reproduction 16(10):2050-2055, 2001. PM: 11574490

PCB, DDT exposure and risk of endometrial cancer
Organochlorines and endometrial cancer risk.
Weiderpass E, Adami HO, Baron JA, Wicklund-Glynn A, Aune M, Atuma S, Persson I. Cancer Epidemiology Biomarkers Prevention. 9(5):487-93. 2000. PM:10815693


Endometriosis

Dioxin exposure and risk of endometriosis
Serum dioxin concentrations and endometriosis: a cohort study in Seveso, Italy.
Eskenazi B, Macarelli P, Warner M, Samuels S, Vercellini P, Olive D, Needham LL, Paterson DB, Brambilla P, Gavoni N, Casalni S, Panazza S, Turner W, Gerthoux PM. Environmental Health Perspectives: 110(7): 629-634. 2002. PM:12117638

Dioxin/ PCB body burden, diabetes and endometriosis
Dioxin/ polychlorinated biphenyl body burden, diabetes and endometriosis: findings in a population-based study in Belgium. Fierens S., Mairesse H., Heilier J-F., De Burbure C., Focant J-F., Eppe G., De Pauw E., Bernard A. Biomarkers 8: 529-534, 2003. PM: 15195683.

PCB exposure and risk of endometriosis
Organochlorine exposure and the risk of endometriosis.
Lebel G, Dodin S, Ayotte P, Marcoux S, Ferron LA, Dewailly E. Fertility and Sterility, 69(2): 221-228. 1998. PM:9496332


Fertility-fecundity

Infant deaths caused by DDT exposure comparable to malaria-related infant deaths. Chen, A. and Rogan, W.J. Nonmalarial infant deaths and DDT use for malaria control. Emerging Infectious Diseases. 9(8):960-964. 2003. PM:12967494

Effect of in utero exposure to DDT on fertility. Cohn, B.A., Cirillo, P.M., Wolff, M.S., Schwingl, P.J., Cohen, R.D., Sholtz, R.I., Ferrara, A., Christianson, R.E., van den Berg, B.J., Siiteri, P.K. DDT and DDE exposure in mothers and time to pregnancy in daughters. The Lancet. 361(9376):2205-2206. 2003. P PM:12842376

Effect of organochlorine exposure on timing of menopause
Organochlorine exposure and age at natural menopause. Cooper GS, Savitz DA, Milikan R, Chiu Kit T. Epidemiology; 2002:13(6):729-733. PM:12410018

PCBs and menstrual cycle characteristics
Polychlorinated biphenyls and menstrual cycle characteristics. Cooper, G.S., Klebanoff, M.A., Promislow, J., Brock, J.W., Longnecker, MP. Epidemiology 16:191-200. 2005. PM: 15703533


Effects of dioxin exposure on menstrual cycle
Serum dioxin concentrations and menstrual cycle characteristics.
Eskenazi B, Warner M, Mocarelli P, Samuels S, Needham LL, Patterson Jr, DG, Lippan S, Vercellini P, Gerthoux PM, Brambilla P, Olive D. American Journal of Epidemiology: 156; 383-392. 2002. PM:12181109

Pesticide use and menstrual cycle characteristics
Pesticide use and menstrual cycle characteristics among premenopausal women in the agricultural health study. Farr S.L., Cooper G.S., Cai J., Savitz D.A., Sandler D.P. American Journal of Epidemiology 160:1194-1204, 2004. PM: 15583372

Factors associated with female infertility
Risk factors for female infertility in an agricultural region. Greenlee, A., Arbuckle, T., and Chyou, P. Epidemiology. 14: 429-436. 2003. PM: 12843768

Bisphenol A exposure linked to chromosomal abnormalities in the mouse oocyte Hunt PA, Koehler KE, Susiarjo M, Hodges CA, Ilagan A, Voigt RC, Thomas S, Thomas BF, Hassold TJ. Bisphenol A exposure causes meiotic aneuploidy in the female mouse. Current Biology. 13(7):546-53; 2003. PM:12676084

Time to pregnancy following paternal pesticide exposure
Reduction in fertility in male greenhouse workers exposed to pesticides.
Petrelli G, Figà-Talamanca I. European Journal of Epidemiology 17:675-677. 2001. PM:12086082

Association between PCB exposure and infertility
Chlorinated hydrocarbons in infertile women.
Gerhard I, Monga B, Krahe J, Runnebaum B. Environmental Research Section A. 80:299-310, 1999. PM:10330303


Immune System

Decreased antibody levels associated with TCDD exposure 20 years after the Seveso Accident
Immunologic effects of dioxin: New results from Seveso and comparison with other studies. Environmental Health Perspectives, 110 (12): 1169-1173. 2002.
Baccarelli, A., Mocarelli, P., Patterson, D.G., Bonzini, M., Pesatori, A., Caporaso, N., Landi, M.T. PM: 12460794

Organochlorine exposure and risk of non-Hodgkin's lymphoma
Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines: ss-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin, and hexachlorobenzene.
Cantor KP, Strickland PT, Brock JW, Bush D, Helzlsouer K, Needham LL, Zahm SH, Comstock GW, Rothman N. Environmental Health Perspectives; 2003 ;111(2):179-84. PM:12573902

Decreased immune parameters in Dutch children exposed to dioxin levels in utero.
Persistent hematological and immunological disturbances in Dutch eight-year-old children associated with perinatal dioxin exposure. ten Tusscher, GW., Steerenberg, PA., van Loveren, H., Vos, JG., vondem Borne, AEGK., Westra, M., vander Slikke, JW., Olie, K., Pluim, H., Koppe, JG. Environmental Health Perspectives, Online 14 May 2003.


Male reproductive tract abnormalities

Paternal pesticide exposure and the risk of birth defects
Pesticide appliers, biocides, and birth defects in rural Minnesota.
Garry, V.F, Schreinemachers, D, Harkins, M, Griffith, J. Environmental Health Perspectives. 104(4):394-9. 1996. PM: 8732949

Paternal pesticide exposure, sex ratio and risk of birth defects
Birth defects, season of conception, and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA.
Garry VF, Harkins ME, Erickson LL, Long-Simpson LK, Holland SE, Burroughs BL. Environ Health Perspectives. 110 Suppl 3:441-9. 2002. PM:12060842

Organochlorine bioaccumulation and cryptorchidism
Is there a correlation between organochlorine compounds and undescended testes?
Hosie, S, Loff, S, Witt, K, Niessen, K, Waag, KL. European Journal of Pediatric Surgery. 10:304-309. 2000. PM:11194541

Maternal DDT/DDE exposure and risk of birth defects in male offspring.
Maternal serum level of 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring. Longnecker MP, Klebanoff MA, Brock JW, Zhou H, Gray KA, Needham LL, Wilcox AJ. American Journal of Epidemiology; 155: 313-322. 2002. PMID: 11836195

Risk factors for cryptorchidism and hypospadias
Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case-Control Study in Newborn Boys. Pierik F., Burdof A., Deddens J., Juttmann R., Weber R. Environmental Health Perspectives. 112:1570-1576, 2004. PM: 15531444

Trends in male reproductive tract surgeries in Great Britain. Toledano M.B., Hansell A.L., Jarup L., Quinn M., Jick S., and Elliott P. Temporal trends in orchidopexy, Great Britain, 1992-1998. Environmental Health Perspectives 111(1):129-32. 2003. PM: 12515691

Maternal occupational exposure to endocrine disrupting chemicals and hypospadias
Risk of hypospadias in relation to maternal occupational exposure to potential endocrine disrupting chemicals.
Vrijheid M, Armstrong B, Dolk H, Van Tongeren M, Botting B. Occupational and Environmental Medicine: 60(8):543-550, 2003. PM: 12883014

Paternal and maternal pesticide exposure and the risk of birth defects
Cryptorchidism and hypospadias in the sons of gardeners and farmers.
Wiedner, IS, Møller H, Jensen TK, Skakkebæk NE. Environmental Health Perspectives. 106(12):793-6. 1998. PM:9831539


Neurodevelopment

Neurodevelopment and prenatal PCB exposure
Prenatal exposure to low-level polychlorinated biphenyls in relation to mental and motor development at 8 months.
Daniels JL, Longnecker MP, Klebanoff MA, Gray KA, Brock JW, Zhou H, Chen A, Needham LL. American Journal of Epidemiology: 157(6):485-492, 2003. PM: 12631537

Effects of fetal exposure to organochlorines on neurodevelopment. Ribas-Fito, N., Cardo, E., Sala, M., Eaulalia de Muga, M., Mazon, C., Verdu, A., Kogevinas, M., Grimalt, J.O., Sunyer, J. Breastfeeding, exposure to organochlorine compounds, and neurodevelopment in infants. Pediatrics. 111(5):e580-e585. 2003. PM:12728113


Ovarian Cancer

Occupation and risk of ovarian cancer
Occupational exposures and the risk of ovarian cancer in Sweden. Shields T, Gridley G, Moradi T, Adami J, Plato N, Dosemeci M. American Journal Indian Medicine; 2002; 42(3):200-13 PM:12210689


Precocious puberty

Phthalates and premature breast development
Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development.
Colón I, Caro D, Bourdony CJ, Rosario O. Environmental Health Perspectives, 108(9):895-900. 2000. PM:11017896

PCB, dioxin-exposure and sexual maturation
Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited.
Den Hond E, Roels HA, Hoppenbrouwers K, Nawrot T, Thijs L, Vandermeulen C, Winneke G, Vanderschueren D, Staessen JA. Environmental Health Perspectives. 110: 771-776.2002. PM:12153757

Pesticide p,p'-DDE exposure and precocious puberty
Sexual precocity after immigration from developing countries to Belgium: evidence of previous exposure to organochlorine pesticides.
Krstevska-Konstantinova M, Charlier C, Craen M, Du Caju M, Heinrichs C, de Beaufort C, Plomteux G, Bourguignon JP. Human Reproduction 16(5):1020-1026, 2001. PM:11331654

Age at menarche and organochlorine exposure
In utero exposure to organochlorines and age at menarche. Vasiliu O., Muttineni J., Karmaus W. Human Reproduction 19(7): 1506-1512, 2004. PM: 15131079

Lead effects on puberty in U.S. girls

Blood lead levels and sexual maturation in U.S. girls: The Third National Health and Nutrition Examination Survey, 1988-94. Environmental Health Perspectives, online February 4, 2003. Wu, T., Buck, GM., Mendola, P.


Prostate cancer

Prostate cancer risk associated with agricultural pesticide use
.
Use of agricultural pesticides and prostate cancer risk in the agricultural health study cohort. Alavanja MC, Samanic C, Dosemeci M, Lubin J, Tarone R, Lynch CF, Knott C, Thomas K, Hoppin JA, Barker J, Coble J, Sandler DP, Blair A. American Journal Epidemiology. 157(9):800-14. 2003 PM:12727674

Increased risk of prostate cancer following exposure to pestides.
Prostate cancer and exposure to pesticides in agricultural settings.
Settimi L, Masina A, Andrion A, Axelson O. International Journal of Cancer. 2003;104(4):458-61. PM:12584743

A meta-analysis of occupational pesticide exposure and prostate cancer

Occupation related pesticide exposure and cancer of the prostate: a meta-analysis.
Van Maele-Fabry G, Willems JL. Occupational and Environmental Medicine: 60(9):634-642, 2003. PM: 12937183

Occupational exposure and risk of prostate cancer and other cancers
A critical review of cancer epidemiology in the petroleum industry, with a meta-analysis of a combined database of more than 350,000 workers. Wong O, Raabe GK. Regulatory Toxicology and Pharmacology 32:78-98. 2000. PM:11029272


Semen quality

Serum PCB levels and semen quality
Decreased human semen quality and organochlorine compounds in blood.
Dallinga, J.W., Moonen, E.J., Dumoulin, J.C., Evers, J.L., Geraedts, J.P., Kleinjans, J.C. Human Reproduction, 17(8): 1973-1979.2002. PM:12151423

DDT and semen quality.
The long-term effects of DDT exposure on semen, fertility and sexual function of malaria vector-control workers in Limpopo Province, South Africa.
Dalvie, M., Myers, J., Thompson, M., Robins, T., Dyer, S., Riebow, J., Molekwa, J., Jeebhay, M., Millar, R., and Kruger, P. Environmental Research. 96: 1-8. 2004. PM: 15261778

PCB, DDE exposure and semen quality
Environmental organochlorines and semen quality: results of a pilot study.
Hauser R, Altshul L, Chen Z, Ryan L, Overstreet J, Schiff I, Christiani DC. Environmental Health Perspectives: 110(3); 229-233. 2002. PM:11882472

Effect of PCB and p,p'-DDE exposure on semen quality. Hauser R, Chen Z, Pothier L, Ryan L, Altshul L. The relationship between human semen parameters and environmental exposure to polychlorinated biphenyls and p,p'-DDE. Environmental Health Perspectives. online 19 May 2003.

Semen indices in insecticide sprayers
A survey of semen indices in insecticide sprayers. Kamijima M., Hibi H., Gotoh M., Taki K-I., Saito I., Wang H., Itohara S., Yamada T., Ichihara G., Shibata E., Nakajima T., Takeuchi Y. Journal of Occupational Health 46: 109-118, 2004. PM: 15090685

Environmental factors and semen quality
Environment, lifestyle and male infertility.
Sharpe RM. Bailliere's Clinical Endocrinology and Metabolism 14(3) 2000. PM:11097788

Geographic variation of U.S. semen quality.
Geographic differences in semen quality of fertile U.S. males.
Swan SH, Brazil C, Drobnis EZ, Liu F, Kruse RL, Hatch M, Redmon JB, Wang C, Overstreet JW, The Study For Future Families Research Group. Environmental Health Perspectives. 111(4):414-20; 2003 PM:12676592

Effects of pesticide exposure on semen quality. Swan, SH., Kruse, RL., Liu, F., Barr, DB., Drobnis, EZ., Redmon, JB., Wang, C., Brazil, Overstreet, JW, & The Study for Future Families Research Group. Semen quality in relation to biomarkers of pesticide exposure. Environmental Health Perspectives, Online June 18, 2003


Sex ratios

Sex Ratio Decline among the Aamjiwnaang First Nation community in Ontario.
Declining Sex Ratio in a First Nation Community. Mackenzie CA, Lockridge A, Keith M. Environmental Health Perspectives 113: 1295-1298, 2005. PM: 16203237

See also Interview with Constanze MacKenzie

Paternal dioxin exposure and offspring sex ratio Paternal concentrations of dioxin and sex ratio of offspring. Mocarelli, P., Gerthoux, P.M., Ferrari, E., Patterson, D.G., Kieszak, S.M., Brambilla, P., Vincoli, N., Signorini, S., Tramacere, P., Carreri, V., Sampson, E.J., Turner, W.E. The Lancet 355:1858-1863, 2000. PM: 10866441.

Parental dioxin exposure and offspring sex ratio
Sex ratios of children of Russian pesticide producers exposed to dioxin.
Ryan JJ, Amirova Z, Carrier G. Environmental Health Perspectives, 110: A699-A701. 2002. PM:12417498

Parental organochlorine exposure and offspring sex ratio
Parental concentration of dichlorodiphenyl dichloroethane and polychlorinated biphenyls in Michigan fish eaters and sex ratio.
Karmaus W, Huang S, Cameron L. Journal of Occupational and Environmental Medicine: 44; 8-13. 2002. PM:11802470


Spontaneous abortion

Pesticides and the risk of spontaneous abortion
An exploratory analysis of the effect of pesticide exposure on the risk of spontaneous abortion in an Ontario farm population.
Arbuckle, TE, Lin, Z, Mery, L.S. Environmental Health Perspectives, 109: 851-857.2002. PM:11564623

Parental pesticide use in the Philippines and the risk of birth defects and spontaneous abortion
Pregnancy outcomes among farming households of Nueva Ecija with conventional pesticide use versus integrated pest management.
Crisostomo, L., Molina, VV. International Journal of Occupational and Environmental Health, 8:232-242. 2002. PM:12358079

Effect of maternal dioxin exposure on birth outcomes. Eskenazi B., Mocorelli P., Warner M., Chee W., Gerthoux P.M., Samuels S., Needham L.L., and Patterson D.G. Maternal serum dioxin levels and birth outcomes in women of Seveso, Italy. Environmental Health Perspectives 60(7):947-953.2003. PM:12782497

DDT and spontaneous abortion
Association of DDT with spontaneous abortion: a case-control study. Korrick SA, Chen C, Damokosh AI, Ni J, Liu X , Cho S, Altshul L, Rayan L, Xu X. Annals of Epidemiology 11(7): 491-496, 2001. PM: 11557181.

Paternal DDT exposure and the risk of reproductive effects.
Reproductive effects of occupational DDT exposure among male malaria control workers.
Salazar-Garcia F, Gallardo-Diaz E, Ceron-Mireles P, Loomis D, Borja-Aburto VH. Environmental Health Perspectives: 112(5):542-547, 2004. PM:15064158

Paternal dioxin exposure, spontaneous abortion and sex ratio
Spontaneous abortion, sex ratio, and paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Schnorr TM, Lawson CC, Whelan EA, Dankovic DA, Deddens JA, Piacitelli LA, Reefhuis J, Sweeney MH, Connally LB, Fingerhut MA. Environmental Health Perspectives. 109(11):1127-1132. 2001. PM:11712997

Birth defects in four U.S wheat-producing states
Birth malformations and other adverse perinatal outcomes in four U.S. wheat-producing states. Schreinemachers, DM. Environmental Health Perspectives, on-line April 1, 2003.

Genetic susceptibility, chemical exposures and birth defects. Shaw GM, Nelson V, Iovannisci D, Finnell R, Lammer EJ. Maternal occupational exposures and biotransformation genotypes as risk factors for selected congenital anomalies. American Journal of Epidemiology, 157: 475-484. 2003. PM: 12631536

Bisphenol A and recurrent miscarriage
Exposure to bisphenol A is associated with recurrent miscarriage. Sugiura-Ogasawara, M., Ozaki, Y., Sonta, S., Makino, T., Suzumori, K. Human Reproduction 20:2325-9. 2005. PM: 15947000


Ogranochlorines and preterm birth.
Preterm birth in relation to maternal organochlorine serum levels. Torres-Arreola, L., Berkowitz, G., Torres-Sánchez, L., López-Cervantes, M., Cebrián, M.E., Uribe, M., and López-Carrillo, L. Annals of Epidemiology 13: 158-62. 2003. PM: 12604158


Testicular cancer

Dietary estrogens and risk of testicular and prostatic cancer
Incidence and mortality of testicular and prostatic cancers in relation to world dietary practices.
Ganmaa D, Li XM, Wang J, Qin LQ, Wang PY, Sato A. International Journal of Cancer 98:262-267. 2002. PM:11857417

Exposure to persistent organic pollutants and risk of testicular cancer
Increased concentrations of polychlorinated biphenyls, hexachlorobenzene and chlordanes in mothers to men with testicular cancer.
Hardell, L., van Bavel, B., Lindström, G.; Carlberg, M.; Dreifaldt, AC, Wijkström, H.; Starkhammer, H., Eriksson, M., Hallquist, A., Kolmert, T. Environmental Health Perspectives, Online 19 December 2002.

PCBs and testicular cancer

Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancer.
Hardell, L., Van Bavel, B., Lindstrom, G., Carlberg, M., Eriksson, M., Dreifaldt, A.C., Wijkstrom, H., Starkhammar, H., Hallquist, A., and Kolmert, T. International Journal of Andrology 27:282–290. 2004. PM: 15379968

Phthalate exposure and risk of testicular cancer
Testicular cancer and occupational exposures with a focus on xenoestrogens in polyvinyl chloride plastics.
Ohlson CG, Hardell L. Chemosphere, 40: 1277-1282. 2000. PM:10739073


Thyroid

Effects of in utero PCB exposure on thyroid function in neonates
Polychlorinated biphenyl (PCB) exposure in relation to thyroid hormone levels in neonates.
Longnecker, MP, Gladen, BC, Patterson, DG, Rogan, WJ. Epidemiology; 11: 249-254. 2000. PM:10784239

PCB exposure and thyroid function in rats
Hepatic enzyme induction and acute endocrine effects of 2,2',3,3',4,6-hexachlorobiphenyl and 2,2'3,4,5,6-hexachlorobiphenyl in prepubertal female rats.
Li M-H, Hsu P-C, Guo YL. Archives Environment Contamination Toxicology. 41:381-385. 2001. PM:11503077



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