Summary of endocrine disruption research January
to June 2007
Inherited effects of endocrine disruptors
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male
Fertility. Anway, M.; Cupp, A.; Uzumcu, M.; and Skinner, M. Science
(308):1466-1469, 2005. PM:
Arctic Seabirds and Pond Contamination
Arctic Seabirds Transport Marine-Derived Contaminants. Blais JM, Kimpe
LE, McMahon D, Keatley BE, Mallory ML, Douglas MS, Smol JP. Science.
309: 445, 2005. PM:
See also Interview
with Dr. Blais
BPA and reproductive health
Endocrine disruptors and reproductive health: The case of bisphenol
A. Maffini, M.V., Rubin, B.S., Sonnenschein, C., Soto, A.M. Molecular
and Cellular Endocrinology 25:179-186. 2006. PM:
of organochlorine compounds in breast milk in Czech mothers.
Cajka, T, Hajslova J. Polychlorinated biphenyls and organochlorine
pesticides in human milk from the locality Prague, Czech Republic: A
comparative study. Bulletin Environmental Contamination and Toxicology.
70:913-919. 2003. PM:12719815
Health concerns in areas of environmental
Incidence of endocrine disease among residents of New York areas of
concern. Carpenter DO, Shen Y, Nguyen T, Le L, Lininger LL. Environmental
Health Perspectives. Suppl. 6: 845-851. 2001. PM:11744502
Bisphenol A and Low Dose Effects Weight of the
evidence evaluation of low-dose reproductive and developmental effects
of Bisphenol A. Gray, G.M., Cohen, J.T., Cunha, G., Hughes,
C., McConnell, E.E., Rhomberg, L., Sipes I.G., Mattison, D. Human and
Ecological Risk Assessment, 10: 875-921, 2004.
Cadmium- the new endocrine disrupter?
Johnson, M.D., Kenney, N., Stoica, A., Hilakivi-Clarke, L., Singh, B.,
Chepko, G., Clarke, R., Sholler, P.F., Lirio, A.A., Foss, C., Reiter,
R., Trock, B., Paik, S., Martin, M. Cadmium mimics the in vivo effects
of estrogen in the uterus and mammary gland. Nature Medicine. Advance
Online Publication. 13 July 2003.
TCDD exposure and birth outcomes
Paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
and birth outcomes of offspring: birth weight, preterm delivery, and
birth defects. Lawson, C., Schnorr, T., Whelan, E., Deddens, J.,
Dankovic, D, Piacitelli, L., Sweeney, M., and Connally, L. Environmental
Health Perspectives. 112(14):1403-1408. PM:
to pesticides and risk of childhood leukemia
Critical windows of exposure to household pesticides and risk of
childhood leukemia. Ma X, Buffler PA, Gunier RB, Dahl G, Smith MT,
Reinier K, Reynolds P. Environ Health Perspect. 2002; 110(9):955-60.
application of coal tar induces tumour formation in mice
Effect of a complex environmental mixture from coal tar containing polycyclic
aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding
and metabolic activation of carcinogenic PAH in mouse epidermis.
Marston CP, Pereira C, Ferguson J, Fischer K, Hedstrom O, Dashwood W-M,
Baird WM. Carcinogenesis 22:1077-1086. 2001. PM:11408352
Maternal sport fish consumption and birth
defects by sex of offspring
Birth defects risk associated with maternal sport fish consumption:
potential effect modification by sex of offspring. Mendola P, Robinson
LK, Buck GM, Druschel CM, Fitzgerald EF, Sever LE, Vena JE. Environmental
Research 97(2):134-141, 2005. PM:
outcomes following in utero exposure to environmental pollutants
Effects of transplacental exposure to environmental pollutants on birth
outcomes in a multiethnic population. Perera, FP., Rauh, V., Tsai,
W., Kinney, P., Camann, D., Barr, D., Bernert, T., Garfinkel, R., Tu,
Y., Diaz, D., Dietrich, J., Whyatt, RM. Environmental Health Perspectives,
111 (2): 201-205; 2003. PM:12573906
exposure via dietary intake
A review of the potential impact of dietary endocrine disruptors on
the consumer. Shaw I, McCully S. International Journal of Food Science
and Technology 37:471-476, 2002.
A. Current Need for a New Risk Assessment
An Extensive New Literature Concerning Low-Dose Effects of Bisphenol
A Shows the Need for a New Risk Assessment. Vom Saal FS and Hughes
C. Environmental Health Perspectives: 113(8):926-933, 2005. PM:
disrupting effects of cigarette smoke and risk of breast cancer
Carcinogenic and endocrine disrupting effects of cigarette smoke and
risk of breast cancer. Band PR, Le ND, Fang R, Deschamps M. Lancet
360(9339):1044, 2002. PM:12383984
Breast cancer risk and pesticide exposure
Breast cancer risk and historical exposure to pesticides from wide-area
applications assessed with GIS. Brody JG., Aschengrau A., McKelvey W.,
Rudel RA., Swartz CH., Kennedy T. Environmental Health Perspectives
112(8):889-897, 2004. PM:
between serum organochlorines and breast cancer. Charlier C,
Albert A, Herman P, Hamoir E, Gaspard U, Meurisse M, Plomteux G. Breast
cancer and serum organochlorine residues. Occupational and Environmental
Medicine. 60:348-351. 2003. PM:12709520
Breast cancer and pesticide use
Pesticide Use and Breast Cancer Risk Among Farmersí Wives in the Agricultural
Health Study. Engel L.S., Hill D.A., Hoppin J.A., Lubin J.H., Lynch
C.F., Pierce J., Samanic C., Sandler D.P., Blair A., Alavanja, M.C.
American Journal of Epidemiology 161: 121-135, 2005. PM:
mammary gland development is sensitive to dioxin exposure
Persistent abnormalities in the rat mammary gland following gestational
and lactational exposure to 2,3,7,8 - tetrachlorodibenzo-p-dioxin (TCDD).
Fenton SE, Hamm JT, Birnbaum LS, Youngblood GL. Toxicological Sciences
(67):63-74, 2002. PM:11961217
to herbicide atrazine and risk of breast and ovarian cancer
Regional assessment of Atrazine exposure and incidence of breast and
ovarian cancers in Kentucky. Hopenhayn-Rich C, Stump ML, Browning
SR. Browning Archives of Environmental Contamination and Toxicology.
42:127-136. 2001. PM:11706377
Breast cancer and agricultural pesticide
Residential proximity to agricultural pesticide use and incidence of
breast cancer in the California Teachers cohort. Reynolds P, Hurley
SE, Goldberg DE, Yerabati S, Gunier RB, Hertz A, Anton-Culver H, Bernstein
L, Deapen D, Horn-Ross PL, Peel D, Pinder R, Ross RK, West D, Wright
WE, Ziogas A. Environmental Research 96: 206-218, 2004. PM:
and breast cancer risk
Organochlorines and breast cancer risk by receptor status, tumor size,
and grade (Canada). Woolcott CG, Aronson KJ, Hanna WM, SenGupta
SK, McCready DR, Sterns EE, Miller AB. Cancer Causes and Control, 12:
395-404, 2001 PM:11545454
PCBs, genetic polymorphisms and breast cancer
Serum Polychlorinated Biphenyls, Cytochrome P-450 1A1 Polymorphisms,
and Risk of Breast Cancer in Connecticut Women. Zhang Y., Piece Wise
J., Holford T., Zie H., Boyle P., Hoar Zahm S., Rusiecki J., Zou K.,
Zhang B., Zhu Y., Owens P., and Zheng T. American Journal of Epidemiology.
160: 1177-1183, 2004. PM:
risk of endometriosis and exposure to dioxins and polychlorinated biphenyls:
a case control study of infertile women. Pauwels A, Schepens PJC, Hooghe
TD, Delbeke L, Brouwer L, Weyler J. Human Reproduction 16(10):2050-2055,
PCB, DDT exposure and
risk of endometrial cancer
Organochlorines and endometrial cancer risk. Weiderpass E, Adami
HO, Baron JA, Wicklund-Glynn A, Aune M, Atuma S, Persson I. Cancer Epidemiology
Biomarkers Prevention. 9(5):487-93. 2000. PM:10815693
exposure and risk of endometriosis
Serum dioxin concentrations and endometriosis: a cohort study in Seveso,
Italy. Eskenazi B, Macarelli P, Warner M, Samuels S, Vercellini
P, Olive D, Needham LL, Paterson DB, Brambilla P, Gavoni N, Casalni
S, Panazza S, Turner W, Gerthoux PM. Environmental Health Perspectives:
110(7): 629-634. 2002. PM:12117638
Dioxin/ PCB body burden, diabetes and endometriosis
Dioxin/ polychlorinated biphenyl body burden, diabetes and endometriosis:
findings in a population-based study in Belgium. Fierens S., Mairesse
H., Heilier J-F., De Burbure C., Focant J-F., Eppe G., De Pauw E., Bernard
A. Biomarkers 8: 529-534, 2003. PM:
exposure and risk of endometriosis
Organochlorine exposure and the risk of endometriosis. Lebel G,
Dodin S, Ayotte P, Marcoux S, Ferron LA, Dewailly E. Fertility and Sterility,
69(2): 221-228. 1998. PM:9496332
Infant deaths caused by DDT exposure comparable
to malaria-related infant deaths. Chen, A. and Rogan, W.J. Nonmalarial
infant deaths and DDT use for malaria control. Emerging Infectious
Diseases. 9(8):960-964. 2003. PM:12967494
Effect of in utero exposure to DDT on fertility.
Cohn, B.A., Cirillo, P.M., Wolff, M.S., Schwingl, P.J., Cohen, R.D.,
Sholtz, R.I., Ferrara, A., Christianson, R.E., van den Berg, B.J., Siiteri,
P.K. DDT and DDE exposure in mothers and time to pregnancy in daughters.
The Lancet. 361(9376):2205-2206. 2003. P PM:12842376
Effect of organochlorine
exposure on timing of menopause
Organochlorine exposure and age at natural menopause. Cooper
GS, Savitz DA, Milikan R, Chiu Kit T. Epidemiology; 2002:13(6):729-733.
and menstrual cycle characteristics
Polychlorinated biphenyls and menstrual cycle characteristics. Cooper,
G.S., Klebanoff, M.A., Promislow, J., Brock, J.W., Longnecker, MP. Epidemiology
16:191-200. 2005. PM:
Effects of dioxin exposure
on menstrual cycle
Serum dioxin concentrations and menstrual cycle characteristics. Eskenazi
B, Warner M, Mocarelli P, Samuels S, Needham LL, Patterson Jr, DG, Lippan
S, Vercellini P, Gerthoux PM, Brambilla P, Olive D. American Journal
of Epidemiology: 156; 383-392. 2002. PM:12181109
Pesticide use and menstrual cycle characteristics
Pesticide use and menstrual cycle characteristics among premenopausal
women in the agricultural health study. Farr S.L., Cooper G.S., Cai
J., Savitz D.A., Sandler D.P. American Journal of Epidemiology 160:1194-1204,
Factors associated with female infertility
Risk factors for female infertility in an agricultural region.
Greenlee, A., Arbuckle, T., and Chyou, P. Epidemiology. 14: 429-436.
Bisphenol A exposure linked to chromosomal abnormalities in the mouse
oocyte Hunt PA, Koehler KE, Susiarjo M, Hodges CA, Ilagan A,
Voigt RC, Thomas S, Thomas BF, Hassold TJ. Bisphenol A exposure causes
meiotic aneuploidy in the female mouse. Current Biology. 13(7):546-53;
Time to pregnancy following paternal pesticide
Reduction in fertility in male greenhouse workers exposed to pesticides.
Petrelli G, Figà-Talamanca I. European Journal of Epidemiology
17:675-677. 2001. PM:12086082
between PCB exposure and infertility
Chlorinated hydrocarbons in infertile women. Gerhard I, Monga B,
Krahe J, Runnebaum B. Environmental Research Section A. 80:299-310,
Decreased antibody levels associated with
TCDD exposure 20 years after the Seveso Accident
Immunologic effects of dioxin: New results from Seveso and comparison
with other studies. Environmental Health Perspectives, 110 (12):
1169-1173. 2002. Baccarelli,
A., Mocarelli, P., Patterson, D.G., Bonzini, M., Pesatori, A., Caporaso,
N., Landi, M.T. PM:
Organochlorine exposure and risk of non-Hodgkin's
Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines:
ss-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin,
and hexachlorobenzene. Cantor
KP, Strickland PT, Brock JW, Bush D, Helzlsouer K, Needham LL, Zahm
SH, Comstock GW, Rothman N. Environmental Health Perspectives; 2003
Decreased immune parameters in Dutch
children exposed to dioxin levels in utero.
Persistent hematological and immunological disturbances in Dutch
eight-year-old children associated with perinatal dioxin exposure.
ten Tusscher, GW., Steerenberg, PA., van Loveren, H., Vos, JG., vondem
Borne, AEGK., Westra, M., vander Slikke, JW., Olie, K., Pluim, H., Koppe,
JG. Environmental Health Perspectives, Online 14 May 2003.
pesticide exposure and the risk of birth defects
Pesticide appliers, biocides, and birth defects in rural Minnesota.
Garry, V.F, Schreinemachers, D, Harkins, M, Griffith, J. Environmental
Health Perspectives. 104(4):394-9. 1996. PM:
pesticide exposure, sex ratio and risk of birth defects
Birth defects, season of conception, and sex of children born to pesticide
applicators living in the Red River Valley of Minnesota, USA. Garry
VF, Harkins ME, Erickson LL, Long-Simpson LK, Holland SE, Burroughs
BL. Environ Health Perspectives. 110 Suppl 3:441-9. 2002. PM:12060842
bioaccumulation and cryptorchidism
Is there a correlation between organochlorine compounds and undescended
testes? Hosie, S, Loff, S, Witt, K, Niessen, K, Waag, KL. European
Journal of Pediatric Surgery. 10:304-309. 2000. PM:11194541
Maternal DDT/DDE exposure and risk of
birth defects in male offspring.
Maternal serum level of 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene
and risk of cryptorchidism, hypospadias, and polythelia among male offspring.
Longnecker MP, Klebanoff MA, Brock JW, Zhou H, Gray KA, Needham LL,
Wilcox AJ. American Journal of Epidemiology; 155: 313-322. 2002. PMID:
Risk factors for cryptorchidism and hypospadias
Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias:
A Case-Control Study in Newborn Boys. Pierik F., Burdof A., Deddens
J., Juttmann R., Weber R. Environmental Health Perspectives. 112:1570-1576,
Trends in male reproductive tract surgeries
in Great Britain. Toledano M.B., Hansell A.L., Jarup L., Quinn
M., Jick S., and Elliott P. Temporal trends in orchidopexy, Great
Britain, 1992-1998. Environmental Health Perspectives 111(1):129-32.
Maternal occupational exposure to endocrine
disrupting chemicals and hypospadias
Risk of hypospadias in relation to maternal occupational exposure to
potential endocrine disrupting chemicals. Vrijheid M, Armstrong
B, Dolk H, Van Tongeren M, Botting B. Occupational and Environmental
Medicine: 60(8):543-550, 2003. PM:
and maternal pesticide exposure and the risk of birth defects
Cryptorchidism and hypospadias in the sons of gardeners and farmers.
Wiedner, IS, Møller H, Jensen TK, Skakkebæk NE. Environmental
Health Perspectives. 106(12):793-6. 1998. PM:9831539
Neurodevelopment and prenatal PCB exposure
Prenatal exposure to low-level polychlorinated biphenyls in relation
to mental and motor development at 8 months. Daniels JL, Longnecker
MP, Klebanoff MA, Gray KA, Brock JW, Zhou H, Chen A, Needham LL. American
Journal of Epidemiology: 157(6):485-492, 2003. PM:
of fetal exposure to organochlorines on neurodevelopment. Ribas-Fito,
N., Cardo, E., Sala, M., Eaulalia de Muga, M., Mazon, C., Verdu, A.,
Kogevinas, M., Grimalt, J.O., Sunyer, J. Breastfeeding, exposure
to organochlorine compounds, and neurodevelopment in infants. Pediatrics.
111(5):e580-e585. 2003. PM:12728113
and risk of ovarian cancer
Occupational exposures and the risk of ovarian cancer in Sweden.
Shields T, Gridley G, Moradi T, Adami J, Plato N, Dosemeci M. American
Journal Indian Medicine; 2002; 42(3):200-13 PM:12210689
and premature breast development
Identification of phthalate esters in the serum of young Puerto Rican
girls with premature breast development. Colón I, Caro D,
Bourdony CJ, Rosario O. Environmental Health Perspectives, 108(9):895-900.
dioxin-exposure and sexual maturation
Sexual maturation in relation to polychlorinated aromatic hydrocarbons:
Sharpe and Skakkebaek's hypothesis revisited. Den Hond E, Roels
HA, Hoppenbrouwers K, Nawrot T, Thijs L, Vandermeulen C, Winneke G,
Vanderschueren D, Staessen JA. Environmental Health Perspectives. 110:
Pesticide p,p'-DDE exposure and precocious
Sexual precocity after immigration from developing countries to Belgium:
evidence of previous exposure to organochlorine pesticides. Krstevska-Konstantinova
M, Charlier C, Craen M, Du Caju M, Heinrichs C, de Beaufort C, Plomteux
G, Bourguignon JP. Human Reproduction 16(5):1020-1026, 2001. PM:11331654
Age at menarche and organochlorine exposure
In utero exposure to organochlorines and age at menarche. Vasiliu O.,
Muttineni J., Karmaus W. Human Reproduction 19(7): 1506-1512, 2004.
Lead effects on puberty in U.S. girls
Blood lead levels and sexual maturation in U.S. girls: The Third
National Health and Nutrition Examination Survey, 1988-94. Environmental
Health Perspectives, online February 4, 2003. Wu, T., Buck, GM., Mendola,
Prostate cancer risk associated with agricultural
Use of agricultural pesticides and prostate cancer risk in the agricultural
health study cohort. Alavanja MC, Samanic C, Dosemeci M, Lubin J,
Tarone R, Lynch CF, Knott C, Thomas K, Hoppin JA, Barker J, Coble J,
Sandler DP, Blair A. American Journal Epidemiology. 157(9):800-14. 2003
risk of prostate cancer following exposure to pestides.
Prostate cancer and exposure to pesticides in agricultural settings.
Settimi L, Masina A, Andrion A, Axelson O. International Journal of
Cancer. 2003;104(4):458-61. PM:12584743
A meta-analysis of occupational pesticide exposure and prostate cancer
Occupation related pesticide exposure and cancer of the prostate: a
meta-analysis. Van Maele-Fabry G, Willems JL. Occupational and Environmental
Medicine: 60(9):634-642, 2003. PM:
Occupational exposure and risk of prostate cancer
and other cancers
A critical review of cancer epidemiology in the petroleum industry,
with a meta-analysis of a combined database of more than 350,000 workers.
Wong O, Raabe GK. Regulatory Toxicology and Pharmacology 32:78-98.
Serum PCB levels and semen quality
Decreased human semen quality and organochlorine compounds in blood.
Dallinga, J.W., Moonen, E.J., Dumoulin, J.C., Evers, J.L., Geraedts,
J.P., Kleinjans, J.C. Human Reproduction, 17(8): 1973-1979.2002. PM:12151423
DDT and semen quality.
The long-term effects of DDT exposure on semen, fertility and sexual
function of malaria vector-control workers in Limpopo Province, South
Africa. Dalvie, M., Myers, J., Thompson, M., Robins, T., Dyer, S.,
Riebow, J., Molekwa, J., Jeebhay, M., Millar, R., and Kruger, P. Environmental
Research. 96: 1-8. 2004. PM:
PCB, DDE exposure and semen quality
Environmental organochlorines and semen quality: results of a pilot
study. Hauser R, Altshul L, Chen Z, Ryan L, Overstreet J, Schiff
I, Christiani DC. Environmental Health Perspectives: 110(3); 229-233.
Effect of PCB and p,p'-DDE exposure on
semen quality. Hauser R, Chen Z, Pothier L, Ryan L, Altshul
L. The relationship between human semen parameters and environmental
exposure to polychlorinated biphenyls and p,p'-DDE. Environmental
Health Perspectives. online 19 May 2003.
Semen indices in insecticide sprayers
A survey of semen indices in insecticide sprayers. Kamijima M., Hibi
H., Gotoh M., Taki K-I., Saito I., Wang H., Itohara S., Yamada T., Ichihara
G., Shibata E., Nakajima T., Takeuchi Y. Journal of Occupational Health
46: 109-118, 2004. PM:
factors and semen quality
Environment, lifestyle and male infertility. Sharpe RM. Bailliere's
Clinical Endocrinology and Metabolism 14(3) 2000. PM:11097788
Geographic variation of U.S. semen quality.
Geographic differences in semen quality of fertile U.S. males. Swan
SH, Brazil C, Drobnis EZ, Liu F, Kruse RL, Hatch M, Redmon JB, Wang
C, Overstreet JW, The Study For Future Families Research Group. Environmental
Health Perspectives. 111(4):414-20; 2003 PM:12676592
Effects of pesticide exposure on semen quality.
Swan, SH., Kruse, RL., Liu, F., Barr, DB., Drobnis, EZ., Redmon, JB.,
Wang, C., Brazil, Overstreet, JW, & The Study for Future Families
Research Group. Semen quality in relation to biomarkers of pesticide
exposure. Environmental Health Perspectives, Online June 18, 2003
Sex Ratio Decline among the Aamjiwnaang First
Nation community in Ontario.
Declining Sex Ratio in a First Nation Community. Mackenzie
CA, Lockridge A, Keith M. Environmental Health Perspectives 113: 1295-1298,
See also Interview
with Constanze MacKenzie
dioxin exposure and offspring sex ratio Paternal concentrations of dioxin
and sex ratio of offspring. Mocarelli, P., Gerthoux, P.M., Ferrari,
E., Patterson, D.G., Kieszak, S.M., Brambilla, P., Vincoli, N., Signorini,
S., Tramacere, P., Carreri, V., Sampson, E.J., Turner, W.E. The Lancet
355:1858-1863, 2000. PM:
Parental dioxin exposure and offspring sex ratio
Sex ratios of children of Russian pesticide producers exposed to dioxin.
JJ, Amirova Z, Carrier G. Environmental Health Perspectives, 110: A699-A701.
Parental organochlorine exposure and offspring
Parental concentration of dichlorodiphenyl dichloroethane and polychlorinated
biphenyls in Michigan fish eaters and sex ratio.
Karmaus W, Huang S, Cameron L. Journal of Occupational and Environmental
Medicine: 44; 8-13. 2002. PM:11802470
Pesticides and the risk of spontaneous abortion
An exploratory analysis of the effect of pesticide exposure on the risk
of spontaneous abortion in an Ontario farm population. Arbuckle,
TE, Lin, Z, Mery, L.S. Environmental Health Perspectives, 109: 851-857.2002.
Parental pesticide use in the Philippines
and the risk of birth defects and spontaneous abortion
Pregnancy outcomes among farming households of Nueva Ecija with conventional
pesticide use versus integrated pest management. Crisostomo, L.,
Molina, VV. International Journal of Occupational and Environmental
Health, 8:232-242. 2002. PM:12358079
Effect of maternal dioxin exposure on birth
outcomes. Eskenazi B., Mocorelli P., Warner M., Chee W., Gerthoux
P.M., Samuels S., Needham L.L., and Patterson D.G. Maternal serum
dioxin levels and birth outcomes in women of Seveso, Italy. Environmental
Health Perspectives 60(7):947-953.2003. PM:12782497
DDT and spontaneous abortion
Association of DDT with spontaneous abortion: a case-control study.
Korrick SA, Chen C, Damokosh AI, Ni J, Liu X , Cho S, Altshul L, Rayan
L, Xu X. Annals of Epidemiology 11(7): 491-496, 2001. PM:
DDT exposure and the risk of reproductive effects.
Reproductive effects of occupational DDT exposure among male malaria
control workers. Salazar-Garcia F, Gallardo-Diaz E, Ceron-Mireles
P, Loomis D, Borja-Aburto VH. Environmental Health Perspectives: 112(5):542-547,
Paternal dioxin exposure, spontaneous abortion
and sex ratio
Spontaneous abortion, sex ratio, and paternal occupational exposure
to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Schnorr TM, Lawson CC, Whelan
EA, Dankovic DA, Deddens JA, Piacitelli LA, Reefhuis J, Sweeney MH,
Connally LB, Fingerhut MA. Environmental Health Perspectives. 109(11):1127-1132.
Birth defects in four U.S wheat-producing
Birth malformations and other adverse perinatal outcomes in four
U.S. wheat-producing states. Schreinemachers, DM. Environmental
Health Perspectives, on-line April 1, 2003.
Genetic susceptibility, chemical exposures
and birth defects. Shaw GM, Nelson
V, Iovannisci D, Finnell R, Lammer EJ. Maternal occupational exposures
and biotransformation genotypes as risk factors for selected congenital
anomalies. American Journal of Epidemiology, 157: 475-484. 2003.
Bisphenol A and recurrent
Exposure to bisphenol A is associated with recurrent miscarriage. Sugiura-Ogasawara,
M., Ozaki, Y., Sonta, S., Makino, T., Suzumori, K. Human Reproduction
20:2325-9. 2005. PM:
Ogranochlorines and preterm birth.
Preterm birth in relation to maternal organochlorine serum levels.
Torres-Arreola, L., Berkowitz, G., Torres-Sánchez, L., López-Cervantes,
M., Cebrián, M.E., Uribe, M., and López-Carrillo, L. Annals
of Epidemiology 13: 158-62. 2003. PM:
estrogens and risk of testicular and prostatic cancer
Incidence and mortality of testicular and prostatic cancers in relation
to world dietary practices. Ganmaa D, Li XM, Wang J, Qin LQ, Wang
PY, Sato A. International Journal of Cancer 98:262-267. 2002. PM:11857417
Exposure to persistent organic pollutants
and risk of testicular cancer
Increased concentrations of polychlorinated biphenyls, hexachlorobenzene
and chlordanes in mothers to men with testicular cancer. Hardell,
L., van Bavel, B., Lindström, G.; Carlberg, M.; Dreifaldt, AC,
Wijkström, H.; Starkhammer, H., Eriksson, M., Hallquist, A., Kolmert,
T. Environmental Health Perspectives, Online 19 December 2002.
PCBs and testicular cancer
Concentrations of polychlorinated biphenyls in blood and the risk for
testicular cancer. Hardell, L., Van Bavel, B., Lindstrom, G., Carlberg,
M., Eriksson, M., Dreifaldt, A.C., Wijkstrom, H., Starkhammar, H., Hallquist,
A., and Kolmert, T. International Journal of Andrology 27:282290.
exposure and risk of testicular cancer
Testicular cancer and occupational exposures with a focus on xenoestrogens
in polyvinyl chloride plastics. Ohlson CG, Hardell L. Chemosphere,
40: 1277-1282. 2000. PM:10739073
of in utero PCB exposure on thyroid function in neonates
Polychlorinated biphenyl (PCB) exposure in relation to thyroid hormone
levels in neonates. Longnecker, MP, Gladen, BC, Patterson, DG, Rogan,
WJ. Epidemiology; 11: 249-254. 2000. PM:10784239
PCB exposure and thyroid function in rats
Hepatic enzyme induction and acute endocrine effects of 2,2',3,3',4,6-hexachlorobiphenyl
and 2,2'3,4,5,6-hexachlorobiphenyl in prepubertal female rats. Li
M-H, Hsu P-C, Guo YL. Archives Environment Contamination Toxicology.
41:381-385. 2001. PM:11503077